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Aerial view showing trees burning on the left hand side of a road and on the right hand side new houses in danger of being engulfed in smoke

Why are El Niños getting stronger? 1000-year-coral record points to climate change

A reconstruction of Pacific Ocean sea surface temperatures adds to the evidence that human-caused warming is boosting El Niño events.

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  • Automated prototyping of genetic codes

    A robotic, cell–free platform rapidly prototypes redesigned genetic codes, enabling the translation of proteins with reassigned codons and non-standard amino acids without altering living genomes.

    • Felix Radford
    • Nayan Sapers
    • George M. Church
    ArticleOpen Access
  • Ultrafast and reference-free sequence discovery in single-cell data

    Malva enables ultrafast, reference-free searching of raw single-cell sequences across millions of cells, transforming static transcriptomic atlases into dynamic resources for understanding the functions of sequences.

    • Daniel León-Periñán
    • Nikos Karaiskos
    • Nikolaus Rajewsky
    ArticleOpen Access
  • Amphibious stem-insect sheds light on colonization of land

    Restudy of a challenging fossil using cross-polarized light imaging and phylogenetic reconstruction identifies Chosha praecursor, a probable early-diverging insect, helping to bridge the longstanding ‘hexapod gap’ in the fossil record.

    • Erik Tihelka
    • Carlos Vásquez
    • Chenyang Cai
    Article
Microscope image of engineered RNA nanostars

Nanoscience and nanotechnology

From programmable RNA architectures to next-generation materials for energy and health care, researchers are harnessing the unusual properties of the nanoscale to tackle some of society’s biggest challenges.
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