Article Publicly Available

Cite this

Integration of cellular bioenergetics with mitochondrial quality control and autophagy

• Bradford G. Hill

  Bradford G. Hill received his PhD in Biochemistry from the University of Louisville. He completed postdoctoral training in mitochondrial biology in the laboratory of Victor Darley-Usmar at the University of Alabama-Birmingham before moving to U of L as an Assistant Professor of Medicine in the Center for Diabetes and Obesity Research. Dr. Hill’s research focuses on understanding the role of intermediary metabolism in cardiovascular health and disease. The long-term objective of these studies is to identify derangements in metabolism that underlie the development of obesity and cardiovascular disease and to target these metabolic processes therapeutically.

  , Gloria A. Benavides

  Gloria A. Benavides holds a BSc in Clinical Chemist, and a MSc and a PhD in Biomedical Chemistry from the Autonomous University of Nuevo Leon, Mexico. She was a Visiting Scholar in the Chemistry Department of Louisiana State University (1998–1999) and the Pharmacognosy Department in The University of Mississippi (2001); a Postdoctoral Researcher in the Departments of Environmental Health Sciences (2004–2007) and Pathology (2007–2011), and is currently a Research Associate in the Pathology Department at University of Alabama at Birmingham (2011–current).

  , Jack R. Lancaster

  Jack R. Lancaster received his PhD in Biochemistry from the University of Tennessee Health Sciences Center, and pursued postdoctoral work at Cornell and Duke universities. He assumed faculty positions in the Department of Chemistry and Biochemistry, Utah State University; Department of Surgery, University of Pittsburgh; Department of Physiology, LSU Health Sciences Center New Orleans; and the Department of Anesthesiology, University of Alabama at Birmingham. His research focus is on the chemical and physical foundations of the biological actions of nitric oxide.

  , Scott Ballinger

  Scott Ballinger received his undergraduate degrees from Texas A&M University and his PhD in Biochemistry from Emory University. He completed postdoctoral training at the University of Vermont’s Genetics and Toxicology Laboratory, as an Environmental Pathology Fellow and as a Department of Energy Alexander Hollaender Distinguished Fellow. He is currently a Professor of Pathology in the Division of Molecular and Cellular Pathology, Department of Pathology and a senior scientist in the Center for Free Radical Biology at the University of Alabama at Birmingham. His laboratory studies the role of the mitochondrion and its genetics upon influencing disease susceptibility with focus upon diseases influenced by the environment, particularly the cardiometabolic diseases.

  , Lou Dell’Italia

  Louis Dell’Italia received his MD and subsequent Internal Medicine training at Georgetown University and his Cardiology Fellowship Training at the University of Texas Health Science Center at San Antonio (UTSA). He served as Cardiology Faculty at UTSA and moved to the University of Alabama-Birmingham (UAB) where he has been since 1988 serving as a staff physician at the Birmingham VA Medical Center and Faculty at the UAB School of Medicine in the Department of Medicine and Division of Cardiovascular Disease. Dr. Dell’Italia’s research focuses on understanding the molecular and cellular mechanisms in the pathophysiology of a pure volume overload of the heart, in particular in patients with mitral regurgitation.

  , Jianhua Zhang

  Jianhua Zhang was trained at University of Texas Medical Center at Dallas for her PhD. She then completed her postdoctoral studies at the Whitehead Institute for Biomedical Research. She was appointed to her first faculty position at University of Cincinnati Medical Center. In 2005 she joined the University of Alabama at Birmingham where she is now an Associate Professor in the Department of Pathology. She leads a research program to understand the mechanisms of apoptosis and autophagy in neurodegeneration.

  and Victor M. Darley-Usmar

  Victor M. Darley-Usmar is presently Professor of Pathology and Director of the UAB Center for Free Radical Biology at UAB. In this role, he is able to combine major research interests in mitochondriology and reactive oxygen and nitrogen species with a pursuit of an understanding of the mechanisms of cell death in cardiovascular disease. He was trained as biochemist at the University of Essex in England and then moved to the University of Oregon to pursue his interests in the structure and function of mitochondrial proteins in human disease. After a period as a lecturer in Japan and a Research Scientist at the Wellcome Research Foundation in London he joined UAB to establish his own research group in the Department of Pathology.