Global collaboration and equitable access to reagents and data are fundamental to decentralized scientific research. This month we highlight some initiatives around the world aimed at democratizing research.

Hurdles are surmountable, that’s the pervasive sense among some established and early-career biomedical scientists about building research capacity across Africa, with Ethiopia as one example. The global research community stands to benefit, too.

Biological figures increasingly originate in the browser.

This Perspective promotes the use of external validation using independent datasets for human neuroimaging studies.

This Article introduces a phospho-switch for allosterically regulating target proteins in response to ERK kinase activity.

Siibra is a software suite for working with diverse human brain atlases. It links data acquired with different modalities and at different resolution, thereby creating a Multilevel Human Brain Atlas.

Imaging of brain-wide vascular activity with BOLD fMRI in combination with calcium imaging at single-cell resolution using MRI-compatible components provides detailed insights into neurovascular coupling in mouse models.

NicheTrans is a multimodal framework that enables translation of spatial data across modalities.

This Registered Report presents the results of a study to evaluate the performance of sequence-based protein localization predictors on a curated test dataset of 3,814 human proteins.

EviAnn surpasses existing genome annotation methods by leveraging gene expression and protein sequence homology evidence to achieve higher accuracy and efficiency.

We share some recent staff updates at Nature Methods.