Fig. 3: Splenocytes from immunized rats respond to the TH peptide and full peptide immunogen, not to the CGRP peptide.
From: Preclinical characterization of an active immunotherapy targeting calcitonin gene-related peptide
a Representative image from ELISpot plate of IFNγ-secreting splenocytes collected from adjuvant control rats, p4796kb-immunized rats, or p5830kb-immunized rats. Splenocytes were either untreated or stimulated with the Th-peptide, CGRP, the full peptide immunogen, or the positive control Concanavalin A. Empty wells (Blank) are also included. b Quantification of spot count per million cells from the IFNγ ELISpot of splenocytes from rats immunized with p4796kb and p5380kb compared to Adjuvant control. Data are presented as means +/− SEM; n = 5 rats per group. *p < 0.05, **p < 0.01.
