OR5M8

Olfactory receptor, family 5, subfamily M, member 8
Identifiers
Symbols	OR5M8 ; OR11-194
External IDs	MGI: 3030865 HomoloGene: 73973 GeneCards: OR5M8 Gene
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • odorant binding Cellular component • plasma membrane • integral component of plasma membrane Biological process • G-protein coupled receptor signaling pathway • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	219484	257916
Ensembl	ENSG00000181371	ENSMUSG00000043267
UniProt	Q8NGP6	Q7TR87
RefSeq (mRNA)	NM_001005282	NM_001011759
RefSeq (protein)	NP_001005282	NP_001011759
Location (UCSC)	Chr 11: 56.49 – 56.49 Mb	Chr 2: 85.99 – 85.99 Mb
PubMed search	[1]	[2]

Olfactory receptor 5M8 is a protein that in humans is encoded by the OR5M8 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199. 
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.  CS1 maint: Multiple names: authors list (link)

External links

• OR5M8 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.