OR4D2

Olfactory receptor, family 4, subfamily D, member 2
Identifiers
Symbols	OR4D2 ; BC2009; OR17-24
External IDs	MGI: 3030297 HomoloGene: 64870 GeneCards: OR4D2 Gene
Gene ontology Molecular function • transmembrane signaling receptor activity • G-protein coupled receptor activity • olfactory receptor activity Cellular component • plasma membrane • integral component of membrane Biological process • G-protein coupled receptor signaling pathway • detection of chemical stimulus involved in sensory perception • detection of chemical stimulus involved in sensory perception of smell Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	124538	258406
Ensembl	ENSG00000255713	ENSMUSG00000093839
UniProt	P58180	Q5SW49
RefSeq (mRNA)	NM_001004707	NM_146411
RefSeq (protein)	NP_001004707	NP_666523
Location (UCSC)	Chr 17: 58.17 – 58.17 Mb	Chr 11: 87.89 – 87.89 Mb
PubMed search	[1]	[2]

Olfactory receptor 4D2 is a protein that in humans is encoded by the OR4D2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199. 
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.  CS1 maint: Multiple names: authors list (link)
• Zody MC, Garber M, Adams DJ, et al. (2006). "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.". Nature 440 (7087): 1045–9. doi:10.1038/nature04689. PMC 2610434. PMID 16625196. 

External links

• OR4D2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.