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JWH-030

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JWH-030
Systematic (IUPAC) name
naphthalen-1-yl-(1-pentylpyrrol- 3-yl)methanone
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 162934-73-8
ATC code  ?
PubChem CID 9971539
Chemical data
Formula C20H21NO 
Mol. mass 291.386 g/mol
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

JWH-030 is a research chemical which is a cannabinoid receptor agonist.[1] It has analgesic effects and is used in scientific research.[2] It is a partial agonist at CB1 receptors, with a Ki of 87nM, making it roughly half the potency of THC.[3] It was discovered and named after Dr. John W. Huffman.

[edit] See also

[edit] References

  1. ^ Lainton JAH, Huffman JW, Martin BR, Compton DR. Tetrahedron Letters. 1995; 36:1401.
  2. ^ Pertwee RG, Griffin, G, Lainton JAH, Huffman JW. European Journal of Pharmacology. 1995; 284:241.
  3. ^ Griffin, G.; Atkinson, P. J.; Showalter, V. M.; Martin, B. R.; Abood, M. E. (1998). "Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3-35Sthio)-triphosphate binding assay in rat cerebellar membranes". The Journal of pharmacology and experimental therapeutics 285 (2): 553–560. PMID 9580597.  edit
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