O-2372
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| Systematic (IUPAC) name | |
| 6-((6aR,10aR)-1-hydroxy-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-3-yl)-6-methyl-1-morpholinoheptan-1-one | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| ATC code | ? |
| PubChem | CID 24848987 |
| Chemical data | |
| Formula | C28H41NO4 |
| Mol. mass | 455.629 g/mol |
| SMILES | eMolecules & PubChem |
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O-2372 is an analgesic cannabinoid derivative created by Organix Inc. for use in scientific research. It has high affinity for both CB1 and CB2 receptors, with Ki values of 1.3nM at CB1 and 0.57nM at CB2, but is only moderately soluble in water compared to other related compounds such as O-2694, which it is a metabolite of.[1]
[edit] See also
[edit] References
- ^ Martin BR, Wiley JL, Beletskaya I, Sim-Selley LJ, Smith FL, Dewey WL, Cottney J, Adams J, Baker J, Hill D, Saha B, Zerkowski J, Mahadevan A, Razdan RK. Pharmacological characterization of novel water-soluble cannabinoids. Journal of Pharmacology and Experimental Therapeutics. 2006 Sep;318(3):1230-9. PMID 16757541
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