Girisopam

Girisopam
Systematic (IUPAC) name
	1-(3-chlorophenyl)- 7,8-dimethoxy- 4-methyl- 5H-2,3-benzodiazepine
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	82230-53-3
ATC code	None
PubChem	CID 71257
ChemSpider	64387
UNII	2LP301A921
Chemical data
Formula	C18H17ClN2O2
Mol. mass	328.79
SMILES	eMolecules & PubChem
	InChI InChI=1S/C18H17ClN2O2/c1-11-7-13-9-16(22-2)17(23-3)10-15(13)18(21-20-11)12-5-4-6-14(19)8-12/h4-6,8-10H,7H2,1-3H3 ; Key:VQYLGVVODFDFNK-UHFFFAOYSA-N ;
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Girisopam^[1] (GYKI-51189) is a drug which is a 2,3-benzodiazepine derivative, related to tofisopam.^[2] It has selective anxiolytic action with no sedative, anticonvulsant or muscle relaxant effects.^[3]^[4]^[5]

[edit] See also

^ US Patent 4322346
^ Psychotropics.dk
^ Andrási F, Horváth K, Sineger E, Berzsenyi P, Borsy J, Kenessey A, Tarr M, Láng T, Kórösi J, Hámori T. Neuropharmacology of a new psychotropic 2,3-benzodiazepine. Arzneimittelforschung. 1987 Oct;37(10):1119-24.
^ Horváth K, Andrási F, Botka P, Hámori T. Anxiolytic profile of girisopam and GYKI 52,322 (EGIS 6775). Comparison with chlordiazepoxide and buspirone. Acta Physiologica Hungarica. 1992;79(2):153-61.
^ Horváth EJ, Salamon C, Bakonyi A, Fekete MI, Palkovits M. [(3)H]-girisopam, a novel selective benzodiazepine for the 2, 3-benzodiazepine binding site. Brain Research. Brain Research Protocols. 1999 Jul;4(2):230-5.

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