Carbetocin
| Systematic (IUPAC) name | |
|---|---|
| (2S)-1-[(3S,6S,9S,12S,15S)-12-[(2S)-butan-2-yl]- 9-(2-carbamoylethyl)-6-(carbamoylmethyl)-15- [(4-hydroxyphenyl)methyl]-16-methyl-5,8,11,14,17- pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane- 3-carbonyl]-N-[(1S)-1-(carbamoylmethylcarbamoyl)- 3-methyl-butyl]pyrrolidine-2-carboxamide |
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| Clinical data | |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Pregnancy cat. | ? |
| Legal status | POM (UK) Not available (U.S.) |
| Routes | Intravenous, intramuscular |
| Pharmacokinetic data | |
| Bioavailability | 80% (IM) |
| Half-life | 40 minutes |
| Identifiers | |
| CAS number | 37025-55-1 |
| ATC code | H01BB03 |
| PubChem | CID 71715 |
| DrugBank | DB01282 |
| ChemSpider | 64765 |
| UNII | 88TWF8015Y |
| KEGG | D07229 |
| Chemical data | |
| Formula | C45H69N11O12S |
| Mol. mass | 988.162 g/mol |
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Carbetocin (Duratocin) is an obstetric drug used to control postpartum hemorrhage, bleeding after giving birth.[1] It is an analogue of oxytocin, and its action is similar to that of oxytocin, such as contraction of the uterus.[2][3]
Carbetocin is available in Canada and the United Kingdom, but not in the United States.
[edit] See also
[edit] References
- ^ "Carbetocin Versus Syntometrine for the Third Stage of Labour". http://clinicaltrials.gov/ct2/show/NCT00499005.
- ^ "Carbetocin (Systemic)". http://www.drugs.com/mmx/carbetocin.html.
- ^ "Carbetocin may be more potent than oxytocin following c-section>". http://www.thedoctorschannel.com/video/3333.html.
[edit] External links
- Carbetocin - Drugs.com
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