OPN1SW

Opsin 1 (cone pigments), short-wave-sensitive
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1KPN
Identifiers
Symbols	OPN1SW; BCP; BOP; CBT
External IDs	OMIM: 613522 MGI: 99438 HomoloGene: 1291 GeneCards: OPN1SW Gene
Gene Ontology Molecular function • receptor activity • G-protein coupled receptor activity • photoreceptor activity Cellular component • photoreceptor outer segment • plasma membrane • integral to plasma membrane Biological process • signal transduction • visual perception • phototransduction • protein-chromophore linkage Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	611	12057
Ensembl	ENSG00000128617	ENSMUSG00000058831
UniProt	P03999	P51491
RefSeq (mRNA)	NM_001708.2	NM_007538.3
RefSeq (protein)	NP_001699.1	NP_031564.1
Location (UCSC)	Chr 7: 128.41 – 128.42 Mb	Chr 6: 29.38 – 29.39 Mb
PubMed search	[1]	[2]

Blue-sensitive opsin is a protein that in humans is encoded by the OPN1SW gene.

See also

• Opsin

Further reading

• Applebury ML, Hargrave PA (1987). "Molecular biology of the visual pigments.". Vision Res. 26 (12): 1881–95. doi:10.1016/0042-6989(86)90115-X. PMID 3303660.
• Swanson WH, Cohen JM (2003). "Color vision.". Ophthalmology clinics of North America 16 (2): 179–203. doi:10.1016/S0896-1549(03)00004-X. PMID 12809157.
• Weitz CJ, Went LN, Nathans J (1992). "Human tritanopia associated with a third amino acid substitution in the blue-sensitive visual pigment". Am. J. Hum. Genet. 51 (2): 444–6. PMC 1682686. PMID 1386496. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1682686/.
• Weitz CJ, Miyake Y, Shinzato K et al. (1992). "Human tritanopia associated with two amino acid substitutions in the blue-sensitive opsin". Am. J. Hum. Genet. 50 (3): 498–507. PMC 1684278. PMID 1531728. //www.ncbi.nlm.nih.gov/pmc/articles/PMC1684278/.
• Oprian DD, Asenjo AB, Lee N, Pelletier SL (1992). "Design, chemical synthesis, and expression of genes for the three human color vision pigments". Biochemistry 30 (48): 11367–72. doi:10.1021/bi00112a002. PMID 1742276.
• Sarkar G, Sommer SS (1989). "Access to a messenger RNA sequence or its protein product is not limited by tissue or species specificity". Science 244 (4902): 331–4. doi:10.1126/science.2565599. PMID 2565599.
• Nathans J, Piantanida TP, Eddy RL et al. (1986). "Molecular genetics of inherited variation in human color vision". Science 232 (4747): 203–10. doi:10.1126/science.3485310. PMID 3485310.
• Shimmin LC, Mai P, Li WH (1997). "Sequences and evolution of human and squirrel monkey blue opsin genes". J. Mol. Evol. 44 (4): 378–82. doi:10.1007/PL00006157. PMID 9089077.
• Scherer SW, Cheung J, MacDonald JR et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205. //www.ncbi.nlm.nih.gov/pmc/articles/PMC2882961/.
• Gunther KL, Neitz J, Neitz M (2006). "A novel mutation in the short-wavelength-sensitive cone pigment gene associated with a tritan color vision defect". Vis. Neurosci. 23 (3–4): 403–9. doi:10.1017/S0952523806233169. PMID 16961973.