
The series draws much inspiration from the original, largely matching its visual style, other than now being presented in widescreen high-definition. The largest change is that the characters now all speak out loud, as opposed to the original Maisy series, in which they only babbled.
The series was made by Karrot Animation and is 2D like the original. The title My Friend Maisy has previously been used for a line of books within the wider Maisy book line.
My Friend Maisy features examples of the following:
- Baths Are Fun: Maisy sings a happy song to herself while washing in the bath and squeaking a rubber duck.
- Counting Sheep: When Maisy and her friends have a sleepover, Charley has trouble sleeping and the others suggest this as means of helping him to fall asleep. He tries it, but it doesn't work, so they move on to other things.
- The Dentist Episode: In "Dentist," Maisy pretends to be a dentist and cleans her friend Charley's teeth.
- Grocery Store Episode: In "Shopping," Maisy goes out shopping with Charley, but ends up losing her shopping list. She remembers that it had milk, eggs and bread on it, but can't remember the last thing, so Charley offers up various suggestions as to what it could have been. She finally remembers that it was cat food she was wanting to buy, while meanwhile Charley ends up purchasing himself all of the things that he had suggested.
- Singing in the Shower: In "Getting Muddy Getting Clean," Maisy sings herself a cheery tune while soaping herself in the bath.
- Suddenly Voiced: The characters now speak out loud in complete sentences, whereas in the original Maisy television series, they just spoke in babble, and was left to a narrator (absent in this series) to explain what is going on. This isn't entirely new, though, as the Maisy First Experiences book releases also had the characters talking to each other in full sentences.
- Thick-Line Animation: The series retains the signature look of the Maisy franchise, characters and objects with thick black outlines, bright colors inside, and vibrant backgrounds. The only real visual difference is that the series is now in widescreen high-definition and the overall color palette is, if anything, even brighter than the original.
- Vague Age: The series retains this characteristic from the original in that the characters appear child-like and do many child-like things, but there are no visible parents and they seem to manage their own affairs, such as running their own baths and Maisy adopts a cat entirely of her own choice. An article regarding the series describes the characters as being "childlike but not children," noting the fact that they are fully independent.
- Washy Watchy: In "Getting Muddy Getting Clean," Maisy places her stuffed toy Panda in the washer to get clean and watches as it and some of her clothes spin around, then goes off to have a bath to get herself clean.
