Chronic Fatigue Syndrome and Myalgic Encephalomyelitis Studies

Latest research

1. Affective dimensions of fatigue in post COVID-19 condition: An interdisciplinary investigation across phenomenology and biomedicine

   • Kristin Zeiler
   • S. Morberg Jämterud
   • R. Levi

   in Phenomenology and the Cognitive Sciences

   Article Open access 13 May 2026

2. Symptom clusters in ME/CFS reflect distinct neuroimmune and autonomic pathophysiological mechanisms: a translational model

   • Lotte Habermann-Horstmeier
   • Lukas M. Horstmeier

   in Journal of Translational Medicine

   Article Open access 28 April 2026

   

3. ME/CFS and Long COVID Demonstrate Similar Bioenergetic Impairment and Recovery Failure on Two-Day Cardiopulmonary Exercise Testing

   • Todd E. Davenport
   • Staci R. Stevens
   • J. Mark Van Ness

   in Clinical & Translational Metabolism

   Article Open access 24 April 2026

   

4. Health, labour market, and social service outcomes for people with Myalgic Encephalomyelitis / Chronic Fatigue Syndrome on a health or disability related benefit: an Aotearoa | New Zealand nationwide cross-sectional study using the integrated data infrastructure

   • Nicholas Bowden
   • Keith McLeod
   • Warren Tate

   in BMC Public Health

   Article Open access 24 April 2026

5. Neuroendocrine signature of ME/CFS: Meta-analytic evidence for bioactive cortisol deficit and exaggerated feedback sensitivity

   • Tae-Wook Woo
   • Yu-Jin Choi
   • Chang-Gue Son

   in Molecular Psychiatry

   Article 23 April 2026

   

6. Neurovascular and synaptic milieu of brain-resident cells in cognitive dysfunction of myalgic encephalomyelitis/chronic fatigue syndrome

   • Huimin Xu
   • Qiaoqi Li
   • Hong Zhu

   in Journal of Translational Medicine

   Article Open access 21 April 2026

7. Identification of novel reproducible combinatorial genetic risk factors for myalgic encephalomyelitis in the DecodeME patient cohort and commonalities with long COVID

   • J. M. Sardell
   • S. Das
   • S. Gardner

   in Journal of Translational Medicine

   Article Open access 21 April 2026

8. PTPRN2 hypomethylation and PHB2-associated miR-153-3p maturation define dual epigenetic features linked to symptom variability in Myalgic encephalomyelitis

   • Lynda Chalder
   • Wesam Elremaly
   • Alain Moreau

   in Journal of Translational Medicine

   Article Open access 20 April 2026

9. Proteomic signatures in cerebrospinal fluid and their clinical associations in patients with ME/CFS

   • Björn Bragée
   • Peng Li
   • Jonas Bergquist

   in Scientific Reports

   Article Open access 03 April 2026

   

10. Genomic interplay between deployment exposures and Gulf War illness in Million Veteran Program participants

    • Dan Qiu
    • Brenda Cabrera-Mendoza
    • Stacey B. Whitbourne

    in Human Genomics

    Article Open access 27 March 2026

    

11. Myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia - overlap, differences, and emerging insights

    • Modra Murovska
    • Angelika Krumina
    • Uldis Berkis

    in Journal of Translational Medicine

    Article Open access 20 February 2026

    

12. Potential application of brain-gut axis-based treatments in Long COVID and ME/CFS: a case-based systematic review

    • Do-Young Kim
    • Jaeyoung Youn
    • In-Hyuk Ha

    in Journal of Translational Medicine

    Article Open access 10 February 2026

    

13. Associated factors and assessment of clinical symptoms including fatigue, insomnia, and gastrointestinal discomfort of chronic fatigue syndrome: a cross-sectional case-control study

    • Fangfang Xie
    • Yanli You
    • Fei Yao

    in Journal of Translational Medicine

    Article Open access 07 February 2026

    

14. A digital platform with activity tracking for energy management support in long COVID: a randomised controlled trial

    • Nilihan EM Sanal-Hayes
    • Lawrence D. Hayes
    • Nicholas F. Sculthorpe

    in Nature Communications

    Article Open access 02 February 2026

    

15. Distinct functional connectivity patterns in myalgic encephalomyelitis and long COVID patients during cognitive fatigue: a 7 Tesla task-fMRI study

    • Maira Inderyas
    • Kiran Thapaliya
    • Leighton Barnden

    in Journal of Translational Medicine

    Article Open access 20 January 2026

    

16. A chronobiology-based protocol for multi-omic mapping of menstrual cycle and diurnal rhythms in ME/CFS and long COVID

    • Natalie Thomas
    • Katherine Huang
    • Christopher W. Armstrong

    in npj Women's Health

    Article Open access 14 January 2026

    

17. Oleoylethanolamide supplementation improves mood and reduces fatigue in veterans with GWI in a 15-week randomized, double-blind, placebo-controlled exploratory clinical trial

    • Laila Abdullah
    • Andrew P. Keegan
    • Michael Mullan

    in Scientific Reports

    Article Open access 09 January 2026

    

18. Virus-induced endothelial senescence as a cause and driving factor for ME/CFS and long COVID: mediated by a dysfunctional immune system

    • Massimo Nunes
    • Loren Kell
    • Etheresia Pretorius

    in Cell Death & Disease

    Article Open access 09 January 2026

    

19. Multi-omics identifies lipid accumulation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome cell lines: a case-control study

    • Daniel Missailidis
    • Christopher W. Armstrong
    • Paul R. Fisher

    in Journal of Translational Medicine

    Article Open access 08 January 2026

    

20. Interoceptive and metacognitive contributors to fatigue in multiple sclerosis: network and mediation analyses

    • Yeşim Eylev Akboğa
    • Nur Nihal Türkel

    in Acta Neurologica Belgica

    Article 07 January 2026