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#

gut-brain-axis

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A genome-resolved metagenomics pipeline replicating the Sharon et al. (2019) gut-brain axis study. Features MEGAHIT de novo co-assembly, Bowtie2 competitive read recruitment, and Anvi'o single-nucleotide variant (SNV) microdiversity profiling.

  • Updated Jul 11, 2026
  • Shell

An integrated computational pipeline for CRISPR-Cas13a (SHERLOCK) malaria diagnostics and trans-kingdom neuro-immune mapping, linking PfK13-driven pathogen detection to microglial homeostatic (CX3CR1/Iba1) set-points and Gut-Brain Axis (GBA) dysregulation.

  • Updated Apr 5, 2026
  • R

Comparative viromics pipeline designed to profile gut viral communities in neurodysbiosis and control cohorts. Implements de novo MEGAHIT assembly, geNomad prediction, CheckV quality assessment, and Bowtie2 read recruitment to characterize gut bacteriophage signatures in humanized mouse models.

  • Updated Jul 16, 2026
  • Shell

PostgreSQL analytics warehouse integrating de novo viral metagenome assembly, CheckV quality control, and geNomad taxonomic/functional annotations to profile condition-associated bacteriophage populations in an ASD vs. TD fecal microbiota transplant gnotobiotic mouse model (Sharon et al. 2019).

  • Updated Jul 23, 2026
  • Python

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