On my platform (macports, py310, py310-virtualenv) the toggleglobalsitepackages is no longer working.
Virtualenvwrapper creates an environment with CPython3Posix. This results in a virtualenv with a pyvenv.cfg file.
This pyvenv.cfg now contains the setting include-system-site-packages = false. It no longer seems to look at the no-global-site-packages.txt which is generated/removed by the toggleglobalsitepackages.

I noticed that in the current master this function is being removed. I think it could be re-implemented to toggle the value in the pyvenv.cfg.

Proposed solution

I think the include-system-site-packages = false should be changed when the toggleglobalsitepackages function is called.

Notes

I'd be happy to prepare a pull request if you agree with the proposed solution. Would a "grep" / "sed" call be the expected implementation (as the other functions are implemented in sh)?