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Request for benchmark sgRNAs and reference results for validating CRISPRme installation

Status: Open.

#110 In pinellolab/CRISPRme;

· orangeSi opened on Jul 23, 2026

Complete-test on chr1 fails with OOM during new_simple_analysis.py despite 32 GB RAM available

Status: Open.

#108 In pinellolab/CRISPRme;

· giseleroch opened on Jul 22, 2026

Allow filtering by maximum total number of edits

enhancementNew feature or requestNew feature or request

Status: Open.

#107 In pinellolab/CRISPRme;

· msejourne opened on Jul 9, 2026

crisprme v2.1.10 failed with sg1617.txt

bugSomething isn't workingSomething isn't working

Status: Open.

#106 In pinellolab/CRISPRme;

· orangeSi opened on Jul 6, 2026

complete-search crashes with bulge=1 on WTN PAM (v2.1.8+ bMax+1 → WTN_2)

Status: Open.

#105 In pinellolab/CRISPRme;

· SamYangBio opened on Jul 3, 2026

Azimuth/scikit-learn scoring error

bugSomething isn't workingSomething isn't working

Status: Open.

#100 In pinellolab/CRISPRme;

· timothy-barry opened on May 12, 2026

Index genome option

enhancementNew feature or requestNew feature or request

Status: Open.

#99 In pinellolab/CRISPRme;

· timothy-barry opened on May 12, 2026

Documentation/code mismatch

bugSomething isn't workingSomething isn't working

Status: Open.

#98 In pinellolab/CRISPRme;

· timothy-barry opened on May 12, 2026

Crisprme Fails to run on the new 1000G 30xNYGC dataset

bugSomething isn't workingSomething isn't working

Status: Open.

#94 In pinellolab/CRISPRme;

· hydriniumh2 opened on Feb 10, 2026