import ipywidgets as widgets
import matplotlib.pyplot as plt
import numpy as np

%matplotlib widget
# or %matplotlib notebook

plt.ioff()

figures = {}

fig, ax = plt.subplots()

def update_plot(value):
    x, y = np.random.random(10), np.random.random(10)
    l = [_ for _ in zip(x, y)]
    
    if len(ax.lines) == 0:  # first call to function
        ax.plot(x,y)
        plt.show()
        
    else:  # all following calls
        ax.lines[0].set_xdata(x)
        ax.lines[0].set_ydata(y)
        fig.canvas.draw_idle()
        
my_widget = widgets.FloatSlider(min=0.1, max=0.9, step=0.1, value=0.5)

my_widget_box = widgets.interactive(update_plot, value=my_widget)
grid = widgets.GridspecLayout(2, 2, layout=widgets.Layout(justify_content='center'))
grid[0, 0] = my_widget_box

display(grid)