Top 23 Python vector-database Projects

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1. llama_index

   1 82 46,198 9.9 Python

   LlamaIndex is the leading framework for building LLM-powered agents over your data.

   

   Project mention: How to Build a RAG Solution with Llama Index, ChromaDB, and Ollama | dev.to | 2025-11-04

   Step 2: Set up LlamaIndex and Chroma DB

2. Stream

   getstream.io featured

   Stream - Scalable APIs for Chat, Feeds, Moderation, & Video. Stream helps developers build engaging apps that scale to millions with performant and flexible Chat, Feeds, Moderation, and Video APIs and SDKs powered by a global edge network and enterprise-grade infrastructure.

   

3. mem0

   2 14 44,973 9.8 Python

   Universal memory layer for AI Agents

   

   Project mention: Show HN: A file-based agent memory framework that works like skill | news.ycombinator.com | 2026-01-06

4. txtai

   3 392 11,978 9.4 Python

   💡 All-in-one AI framework for semantic search, LLM orchestration and language model workflows

   

   Project mention: The AI-Native GraphDB + GraphRAG + Graph Memory Landscape & Market Catalog | dev.to | 2025-10-26

   GitHub: https://github.com/neuml/txtai

5. cognee

   4 13 10,753 9.9 Python

   Memory for AI Agents in 6 lines of code

   

   Project mention: The AI-Native GraphDB + GraphRAG + Graph Memory Landscape & Market Catalog | dev.to | 2025-10-26

   URLs: https://github.com/topoteretes/cognee (hosted at cognee.ai / Cogwit)

6. LEANN

   5 4 7,977 9.7 Python

   RAG on Everything with LEANN. Enjoy 97% storage savings while running a fast, accurate, and 100% private RAG application on your personal device.

   

   Project mention: First lightweight local semantic search MCP for Claude Code | news.ycombinator.com | 2025-08-15

   @Berkeley SkyLab, we’re the first to bring semantic search to Claude Code with a fully local index in a novel, lightweight structure — check it out at LEANN(https://github.com/yichuan-w/LEANN).

7. deep-searcher

   6 2 7,282 9.0 Python

   Open Source Deep Research Alternative to Reason and Search on Private Data. Written in Python.

   

   Project mention: Deep Searcher, Open source deep researcher on your private data | news.ycombinator.com | 2025-02-21

   github https://github.com/zilliztech/deep-searcher

8. airweave

   7 4 5,523 10.0 Python

   Context retrieval for AI agents across apps and databases

   

   Project mention: Launch HN: Airweave (YC X25) – Let agents search any app | news.ycombinator.com | 2025-09-30

9. InfluxDB

   www.influxdata.com featured

   InfluxDB – Built for High-Performance Time Series Workloads. InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now.

   

10. pixeltable

    8 7 1,526 9.7 Python

    Data Infrastructure providing a declarative, incremental approach for multimodal AI workloads.

    

    Project mention: Stop Gluing Data Infrastructure Tools: Build Multimodal AI Workloads and Application with One Declarative Python SDK | dev.to | 2025-07-06

    Star us on GitHub: https://github.com/pixeltable/pixeltable

11. raptor

    9 5 1,485 5.7 Python

    The official implementation of RAPTOR: Recursive Abstractive Processing for Tree-Organized Retrieval

    

    Project mention: Graph RAG의 모든 것 | dev.to | 2025-04-20

    3.2. RAPTOR: Recursive Abstractive Processing for Tree-Organized Retrieval (Stanford Univ, 2024)

12. pymilvus

    10 2 1,320 9.4 Python

    Python SDK for Milvus Vector Database

    

13. SeaGOAT

    11 7 1,242 9.5 Python

    local-first semantic code search engine

    

14. qdrant-client

    12 2 1,191 8.5 Python

    Python client for Qdrant vector search engine

    

15. OpenContracts

    13 2 1,120 9.9 Python

    Enterprise-grade and API-first LLM workspace for unstructured documents, including data extraction, redaction, rights management, prompt playground, and more!

    

16. mcp-memory-service

    14 1 1,045 9.9 Python

    Stop re-explaining your project to AI every session. Automatic context memory for Claude, VS Code, Cursor, and 13+ AI tools.

    

    Project mention: Supercharging Productivity with Cursor AI: A React Developer's Guide to MCP Servers and JSON Prompts | dev.to | 2025-04-17

    Key Takeaway: cursor10x-mcp and Repomix excel for speed and context. MCP Memory Service is great for quick wins, and Pieces organizes prompts. But tools alone don’t cut it—prompts are the real magic.

17. NeumAI

    15 2 861 8.7 Python

    Neum AI is a best-in-class framework to manage the creation and synchronization of vector embeddings at large scale.

    

18. rag-demystified

    16 3 854 8.2 Python

    An LLM-powered advanced RAG pipeline built from scratch

    

19. llmflows

    17 1 706 0.0 Python

    LLMFlows - Simple, Explicit and Transparent LLM Apps

    

20. vectordb

    18 1 632 7.9 Python

    A Python vector database you just need - no more, no less. (by jina-ai)

    

21. langchain-chatbot

    19 1 437 2.9 Python

    AI Chatbot for analyzing/extracting information from data in conversational format.

    

22. GradCache

    20 1 420 4.5 Python

    Run Effective Large Batch Contrastive Learning Beyond GPU/TPU Memory Constraint

    

23. redis-vl-python

    21 1 361 9.2 Python

    Redis Vector Library (RedisVL) -- the AI-native Python client for Redis.

    

24. vector-db-benchmark

    22 6 344 8.2 Python

    Framework for benchmarking vector search engines

    

25. vicinity

    23 2 324 5.4 Python

    Lightweight Nearest Neighbors with Flexible Backends (by MinishLab)

    

26. SaaSHub

    www.saashub.com featured

    SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives

    

Python vector-database related posts

• The Database Zoo: Vector Databases and High-Dimensional Search

  5 projects | dev.to | 25 Nov 2025

• Search Types in Cognee

  1 project | dev.to | 20 Oct 2025

• Cognee: Building the Next Generation of Memory for AI Agents (OSS)

  1 project | dev.to | 17 Oct 2025

• Launch HN: Airweave (YC X25) – Let agents search any app

  1 project | news.ycombinator.com | 30 Sep 2025

• Show HN: Vectorless RAG

  6 projects | news.ycombinator.com | 27 Aug 2025

• Show HN: Airweave – Let agents search any app

  1 project | news.ycombinator.com | 12 May 2025

• Ingest (almost) any non-PDF document in a vector database, effortlessly

  4 projects | dev.to | 25 Apr 2025
• A note from our sponsor - InfluxDB
  www.influxdata.com | 7 Jan 2026

  InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now. Learn more →

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