Corbadrine
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(Redirected from Nordefrin)
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| Systematic (IUPAC) name | |
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4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol
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| Identifiers | |
| CAS Number | 829-74-3  |
| ATC code | none |
| PubChem | CID 164739 |
| IUPHAR/BPS | 508 |
| DrugBank | DB06707  |
| ChemSpider | 144416 |
| UNII | V008L6478D |
| KEGG | D02388 |
| ChEMBL | CHEMBL677 |
| Chemical data | |
| Formula | C9H13NO3 |
| Molar mass | 183.204 g/mol |
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Corbadrine (INN; marketed as Neo-Cobefrine), also known as levonordefrin (USAN) and α-methylnorepinephrine, is a catecholamine sympathomimetic used as a topical nasal decongestant and vasoconstrictor in dentistry in the United States,[1][2] (usually in a pre-mixed solution with local anesthetics, such as mepivacaine).[3]
Corbadrine is also a metabolite of the antihypertensive drug methyldopa,[4] and plays a role in its pharmacology and effects.
See also[edit]
References[edit]
- ^ Dr. Ian Morton; I.K. Morton; Judith M. Hall (31 October 1999). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 164–. ISBN 978-0-7514-0499-9.
- ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 275–. ISBN 978-3-88763-075-1.
- ^ "DailyMed — Search results for levonordefrin". DailyMed. Retrieved 20 February 2016.
- ^ Sjoerdsma, A; Vendsalu, A; Engelman, K; Watts, D (1 October 1963). "Studies on the Metabolism and Mechanism of Action of Methyldopa". Circulation 28 (4): 492–502. doi:10.1161/01.CIR.28.4.492.
External links[edit]
- Nordefrin at the US National Library of Medicine Medical Subject Headings (MeSH)
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