Guanabenz
From Wikipedia, the free encyclopedia
 |
This article needs additional citations for verification. (September 2014) (Learn how and when to remove this template message) |
 |
|
 |
|
| Systematic (IUPAC) name | |
|---|---|
|
2-(2,6-dichlorobenzylidene)hydrazinecarboximidamide
|
|
| Clinical data | |
| Drugs.com | Consumer Drug Information |
| MedlinePlus | a686003 |
| Pregnancy category |
|
| Pharmacokinetic data | |
| Protein binding | 90% |
| Biological half-life | 6 hours |
| Identifiers | |
| CAS Number | 5051-62-7 |
| ATC code | none |
| PubChem | CID 5702063 |
| IUPHAR/BPS | 5443 |
| DrugBank | DB00629  |
| ChemSpider | 4642445 |
| UNII | GGD30112WC |
| KEGG | D04375 |
| ChEMBL | CHEMBL420 |
| Chemical data | |
| Formula | C8H8Cl2N4 |
| Molar mass | 231.081 g/mol |
|
|
|
|
| (verify) |
Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist of the alpha-2 adrenergic receptor that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).[1][2]
The most common side effects during guanabenz therapy are dizziness, drowsiness, dry mouth, headache and weakness.
Guanabenz can make one drowsy or less alert, therefore driving or operating dangerous machinery is not recommended.
See also[edit]
References[edit]
- ^ Walker BR, Hare LE, Deitch MW (1982). "Comparative antihypertensive effects of guanabenz and clonidine". The Journal of International Medical Research 10: 6–14. PMID 7037502.
- ^ Bonham AC, Trapani AJ, Portis LR, Brody MJ (1984). "Studies on the mechanism of the central antihypertensive effect of guanabenz and clonidine". Journal of Hypertension Supplement 2: S543–6.
|
 |
This antihypertensive-related article is a stub. You can help Wikipedia by expanding it. |
