Bamifylline

Bamifylline
Names
	IUPAC name 8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,6-dione
Identifiers
CAS Number	2016-63-9
ChEMBL	ChEMBL2110760
ChemSpider	15401
Jmol 3D model	Interactive image
PubChem	16229
UNII	ZTY15D026H
	InChI InChI=1S/C20H27N5O3/c1-4-24(12-13-26)10-11-25-16(14-15-8-6-5-7-9-15)21-18-17(25)19(27)23(3)20(28)22(18)2/h5-9,26H,4,10-14H2,1-3H3 Key: VVUYEFBRTFASAH-UHFFFAOYSA-N ; InChI=1/C20H27N5O3/c1-4-24(12-13-26)10-11-25-16(14-15-8-6-5-7-9-15)21-18-17(25)19(27)23(3)20(28)22(18)2/h5-9,26H,4,10-14H2,1-3H3 Key: VVUYEFBRTFASAH-UHFFFAOYAJ ;
	SMILES O=C2N(c1nc(n(c1C(=O)N2C)CCN(CC)CCO)Cc3ccccc3)C ;
Properties
Chemical formula	C20H27N5O3
Molar mass	385.46008
Pharmacology
ATC code	R03DA08 (WHO)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Bamifylline is a drug of the xanthine chemical class which acts as a selective adenosine A₁ receptor antagonist.^[1]^[2]

References[edit]

^ Tomai F, Crea F, Gaspardone A, Versaci F, De Paulis R, Polisca P, Chiariello L, Gioffrè PA (June 1996). "Effects of A1 adenosine receptor blockade by bamiphylline on ischaemic preconditioning during coronary angioplasty". European Heart Journal 17 (6): 846–53. doi:10.1093/oxfordjournals.eurheartj.a014965. PMID 8781823.
^ Kofman, J.; Grosclaude, M.; Ouechni, M. M.; Perrin-Fayolle, M. (1982). "Comparative effects of bamifylline and theophylline on allergenic bronchospasm induced by the provocative inhalation test : Double-blind cross-over study". Le Poumon et le coeur 38 (3): 197–202. PMID 6752929.

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