AM-087
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| Systematic (IUPAC) name | |
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(6aR,10aR)-3-(2-methyl-6-bromohex-2-yl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
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| Identifiers | |
| CAS Number | 152674-96-9  |
| PubChem | CID 10717065 |
| ChemSpider | 8892405 |
| ChEMBL | CHEMBL199561 |
| Chemical data | |
| Formula | C23H33BrO2 |
| Molar mass | 421.410 g/mol |
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AM-087 (part of the AM cannabinoid series) is an analgesic drug which acts as a cannabinoid agonist.[1] It is a derivative of Δ8THC substituted on the 3-position side chain. AM-087 is a potent CB1 agonist with a Ki of 0.43nM, making it around 100x more potent than THC itself. This is most likely due to the bulky bromine substituent on the side chain.[2]
See also[edit]
References[edit]
- ^ Martin, Billy R.; Compton, David R.; Semus, Simon F.; Lin, Sonyuan; Marciniak, Gilbert; Grzybowska, Jolanta; Charalambous, Avgui; Makriyannis, Alexandros (1993). "Pharmacological evaluation of iodo and nitro analogs of Δ8-THC and Δ9-THC". Pharmacology Biochemistry and Behavior 46 (2): 295–301. doi:10.1016/0091-3057(93)90356-X. ISSN 0091-3057.
- ^ Charalambous A, et al. Pharmacological evaluation of halogenated delta 8-THC analogs. Pharmacology, Biochemistry and Behaviour. 1991 Nov;40(3):509-12. PMID 1666915
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