MRGPRX3

MAS-related GPR, member X3
Identifiers
Symbols	MRGPRX3 ; GPCR; MRGX3; SNSR1; SNSR2
External IDs	OMIM: 607229 MGI: 3644999 HomoloGene: 79615 IUPHAR: 158 GeneCards: MRGPRX3 Gene
Gene ontology
Molecular function	• G-protein coupled receptor activity;
Cellular component	• integral component of plasma membrane;
Biological process	• G-protein coupled receptor signaling pathway;
	Sources: Amigo / QuickGO
Orthologs
	v; t; e;

Mas-related G-protein coupled receptor member X3 is a protein that in humans is encoded by the MRGPRX3 gene.^[1]^[2]

References[edit]

^ Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ (Sep 2001). "A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons". Cell 106 (5): 619–32. doi:10.1016/S0092-8674(01)00483-4. PMID 11551509.
^ "Entrez Gene: MRGPRX3 MAS-related GPR, member X3".

Lembo PM, Grazzini E, Groblewski T, et al. (2002). "Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs.". Nat. Neurosci. 5 (3): 201–9. doi:10.1038/nn815. PMID 11850634.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Kaisho Y, Watanabe T, Nakata M, et al. (2005). "Transgenic rats overexpressing the human MrgX3 gene show cataracts and an abnormal skin phenotype.". Biochem. Biophys. Res. Commun. 330 (3): 653–7. doi:10.1016/j.bbrc.2005.03.027. PMID 15809047.

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