Metergoline

Metergoline
Systematic (IUPAC) name
	{[(8β)-1,6-dimethylergolin-8-yl]methyl}carbamate
Identifiers
CAS Number	17692-51-2
ATC code	G02CB05 (WHO)
PubChem	CID 28693
IUPHAR/BPS	133
ChemSpider	26687
UNII	1501393LY5
ChEMBL	CHEMBL19215
Chemical data
Formula	C25H29N3O2
Molar mass	403.52 g/mol
	SMILES O=C(OCc1ccccc1)NC[C@@H]3C[C@@H]4c5cccc2c5c(cn2C)C[C@H]4N(C3)C ;
	InChI InChI=1S/C25H29N3O2/c1-27-14-18(13-26-25(29)30-16-17-7-4-3-5-8-17)11-21-20-9-6-10-22-24(20)19(12-23(21)27)15-28(22)2/h3-10,15,18,21,23H,11-14,16H2,1-2H3,(H,26,29)/t18-,21+,23+/m0/s1 ; Key:WZHJKEUHNJHDLS-QTGUNEKASA-N ;
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Metergoline is a psychoactive drug of the ergoline chemical class which acts as a ligand for various serotonin and dopamine receptors.^[1]^[2]

References[edit]

^ Hamon M, Mallat M, Herbet A, et al. (February 1981). "[3H]Metergoline: a new ligand of serotonin receptors in the rat brain". Journal of Neurochemistry 36 (2): 613–26. doi:10.1111/j.1471-4159.1981.tb01634.x. PMID 7463079.
^ Miller KJ, King A, Demchyshyn L, Niznik H, Teitler M (1992). "Agonist activity of sumatriptan and metergoline at the human 5-HT_1D beta receptor: further evidence for a role of the 5-HT_1D receptor in the action of sumatriptan". Eur. J. Pharmacol. 227 (1): 99–102. doi:10.1016/0922-4106(92)90149-P. PMID 1330643.

Metergoline at the US National Library of Medicine Medical Subject Headings (MeSH)

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