Praktolol

Praktolol
(IUPAC) ime
	(RS)-N- {4-[2-hidroksi-3-(izopropilamino)propoksi]fenil}acetamid
Klinički podaci
Identifikatori
CAS broj	6673-35-4
ATC kod	C07AB01
PubChem	4883
DrugBank	DB01297
ChemSpider	4715
UNII	SUG9176GRW
KEGG	D05587
ChEBI	CHEBI:258351
ChEMBL	CHEMBL6995
Hemijski podaci
Formula	C14H22N2O3
Mol. masa	266,336 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C14H22N2O3/c1-10(2)15-8-13(18)9-19-14-6-4-12(5-7-14)16-11(3)17/h4-7,10,13,15,18H,8-9H2,1-3H3,(H,16,17) ; Key: DURULFYMVIFBIR-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Practolol (Eraldin, Dalzic, Praktol, Cardiol, Pralon, Cordialina, Eraldina, Teranol) selektivni je beta blokator koji je korišten u lečenju srčanih aritmija. Praktolol nije više u upotrebi jer je veoma toksičan uprkos toga što je hemijski veoma sličan sa propanololom.^[6]

Nuspojave[uredi - уреди]

Nuspojave ovog leka su tipične za beta blokatore: bronhokonstrikcija, zatajenje srca, zamor, depresija i hipoglikemija.^[7]

Zabrana[uredi - уреди]

Praktolol je zabranjen u Indiji.^[8]

Reference[uredi - уреди]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. doi:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. doi:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). "Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG". Yeast 17 (1): 48–55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. doi:10.1093/nar/gkr777. PMID 21948594. edit
↑ British Medical Journal, March 15, 1975
↑ Rod Flower; Humphrey P. Rang; Maureen M. Dale; Ritter, James M. (2007). Rang & Dale's pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-06911-5.
↑ "Drugs banned in India". Central Drugs Standard Control Organization, Dte.GHS, Ministry of Health and Family Welfare, Government of India. http://cdsco.nic.in/html/drugsbanned.html. pristupljeno 17. 9. 2013..

Литература[uredi - уреди]

Rod Flower; Humphrey P. Rang; Maureen M. Dale; Ritter, James M. (2007). Rang & Dale's pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-06911-5.

Spoljašnje veze[uredi - уреди]

	Portal Medicina
	Portal Hemija

Molimo Vas, obratite pažnju na važno upozorenje u vezi tema o zdravlju (medicini).

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. doi:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. doi:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Joanne Wixon, Douglas Kell (2000). "Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG". Yeast 17 (1): 48–55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[5] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. doi:10.1093/nar/gkr777. PMID 21948594. edit

[6] British Medical Journal, March 15, 1975

[Rang.26Dale6th-7] Rod Flower; Humphrey P. Rang; Maureen M. Dale; Ritter, James M. (2007). Rang & Dale's pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-06911-5.

[ban-8] "Drugs banned in India". Central Drugs Standard Control Organization, Dte.GHS, Ministry of Health and Family Welfare, Government of India. http://cdsco.nic.in/html/drugsbanned.html. pristupljeno 17. 9. 2013..

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Oct	NOV	Dec
	02
2014	2015	2016

Praktolol

Sadržaj/Садржај

Nuspojave[uredi - уреди]

Zabrana[uredi - уреди]

Reference[uredi - уреди]

Литература[uredi - уреди]

Spoljašnje veze[uredi - уреди]

Navigacijski meni

Lični/osobni alati

Imenski prostori

Varijante

Pregledi

Više

Traži-Тражи

Orijentacija-Оријентација

interakcija - интеракција

Ispis/извоз

Alatke-Алатке

Drugi jezici / Други језици