Dexchlorpheniramine

Chlorpheniramine
Systematic (IUPAC) name
	(3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-3-ylpropan-1-amine
Clinical data
Trade names	Chlor-trimeton
AHFS/Drugs.com	monograph
MedlinePlus	a682543
Routes of; administration	Oral
Legal status
Legal status	AU: S4 (Prescription only);
Identifiers
CAS Number	25523-97-1
ATC code	R06AB02 (WHO)
PubChem	CID 33036
IUPHAR/BPS	1210
DrugBank	DB01114
ChemSpider	30576
UNII	3Q9Q0B929N
KEGG	D07803
ChEBI	CHEBI:4464
ChEMBL	CHEMBL1201353
Chemical data
Formula	C16H19ClN2
Molar mass	274.788 g/mol
	SMILES Clc1ccc(cc1)[C@@H](c2ncccc2)CCN(C)C ;
	InChI InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3/t15-/m0/s1 ; Key:SOYKEARSMXGVTM-HNNXBMFYSA-N ;
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Dexchlorpheniramine (trade name Polaramine) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.^[1]^[2] It is the pharmacologically active dextrorotatory isomer of chlorpheniramine.

References[edit]

^ Theunissen, E. L.; Vermeeren, A.; Ramaekers, J. G. (2006). "Repeated-dose effects of mequitazine, cetirizine and dexchlorpheniramine on driving and psychomotor performance". British Journal of Clinical Pharmacology 61 (1): 79–86. doi:10.1111/j.1365-2125.2005.02524.x. PMC 1884990. PMID 16390354.
^ Ortíz San Román, L.; Sanavia Morán, E.; Campos Domínguez, M.; Peinador García, M. M. (2013). "Síndrome anticolinérgico por dexclorfeniramina como causa de retención urinaria". Anales de Pediatría 79 (6): 400–1. doi:10.1016/j.anpedi.2013.02.014. PMID 23680058.

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