Rimiterol

Rimiterol
Systematic (IUPAC) name
	4-{(S)-hydroxy[(2R)-piperidin-2-yl]methyl}benzene-1,2-diol
Identifiers
CAS Number	32953-89-2
ATC code	R03AC05 (WHO)
PubChem	CID 36283
ChemSpider	33366
UNII	26GIW6ZLPH
ChEMBL	CHEMBL1097630
Chemical data
Formula	C12H17NO3
Molar mass	223.268 g/mol
	SMILES O[C@@H](c1ccc(O)c(O)c1)[C@@H]2NCCCC2 ;
	InChI InChI=1S/C12H17NO3/c14-10-5-4-8(7-11(10)15)12(16)9-3-1-2-6-13-9/h4-5,7,9,12-16H,1-3,6H2/t9-,12+/m1/s1 ; Key:IYMMESGOJVNCKV-SKDRFNHKSA-N ;
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Rimiterol (INN/USAN) is a third-generation^[1] short-acting^[2]^[3] β₂ agonist.

Synthesis[edit]

G. H. Sankey, K. D. E. Whiting, DE 2024049; idem, US 3910934 (1970, 1975 to 3M); C. Kaiser, S. T. Ross, DE 2047937; idem, US 3705169 (1971, 1972 to SK & F); G. H. Sankey, K. D. E. Whiting, J. Heterocycl. Chem. 9, 1049 (1972).

References[edit]

^ Palma-Carlos, A. G.; Palma-Carlos, G. S. (1986). "Beta-2-agonists of Third Generation". Allergie et Immunologie 18 (4): 31–32, 35. PMID 2899434.
^ Lai, CK; Twentyman, OP; Holgate, ST (October 1989). "The Effect of an Increase in Inhaled Allergen Dose After Rimiterol Hydrobromide on the Occurrence and Magnitude of the Late Asthmatic Response and the Associated Change in Nonspecific Bronchial Responsiveness". The American Review of Respiratory Disease 140 (4): 917–23. PMID 2572192. |access-date= requires |url= (help)
^ Ydreborg, SO; Svedmyr, N; Thiringer, G (April 1977). "Comparison of Rimiterol and Terbutaline, Given by Aerosol, in a Long-term Study". Scandinavian Journal of Respiratory Diseases 58 (2): 117–24. PMID 16339. |access-date= requires |url= (help)

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[1] Palma-Carlos, A. G.; Palma-Carlos, G. S. (1986). "Beta-2-agonists of Third Generation". Allergie et Immunologie 18 (4): 31–32, 35. PMID 2899434.

[2] Lai, CK; Twentyman, OP; Holgate, ST (October 1989). "The Effect of an Increase in Inhaled Allergen Dose After Rimiterol Hydrobromide on the Occurrence and Magnitude of the Late Asthmatic Response and the Associated Change in Nonspecific Bronchial Responsiveness". The American Review of Respiratory Disease 140 (4): 917–23. PMID 2572192. |access-date= requires |url= (help)

[3] Ydreborg, SO; Svedmyr, N; Thiringer, G (April 1977). "Comparison of Rimiterol and Terbutaline, Given by Aerosol, in a Long-term Study". Scandinavian Journal of Respiratory Diseases 58 (2): 117–24. PMID 16339. |access-date= requires |url= (help)

[1]

[2]

[3]

Mar	APR	May
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2015	2016	2017

Rimiterol

Synthesis[edit]

References[edit]

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