Metomidate
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| Systematic (IUPAC) name | |
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methyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate
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| Legal status | |
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| Identifiers | |
| CAS Number | 5377-20-8  |
| ATCvet code | QN05CM94 (WHO) |
| PubChem | CID 21474 |
| ChemSpider | 20182  |
| UNII | Z18ZYL8Y51 |
| ChEMBL | CHEMBL494039 |
| Chemical data | |
| Formula | C13H14N2O2 |
| Molar mass | 230.263 g/mol |
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Metomidate is a non-barbiturate imidazole that was discovered by Janssen Pharmaceutica in 1965[1] and under the names (Hypnodil, Nokemyl) is sold as a sedative-hypnotic drug used in Europe to treat humans and for veterinary purposes.[2]
11C-labelled metomidate (11C-metomidate), may be used with positron emission tomography (PET). For instance, to detect tumors of adrenocortical origin.[3][4]
See also[edit]
References[edit]
- ^ BE Patent 662474
- ^ Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 683. ISBN 978-3-88763-075-1. Retrieved 27 October 2011.
- ^ Khan TS; Sundin A; Juhlin C; Långström B; et al. (2003). "11C-metomidate PET imaging of adrenocortical cancer". European Journal of Nuclear Medicine and Molecular Imaging 30 (3): 403–410. doi:10.1007/s00259-002-1025-9. PMID 12634969.
- ^ Minn H; Salonen A; Friberg J; Roivainen A; et al. (June 2004). "Imaging of adrenal incidentalomas with PET using (11)C-metomidate and (18)F-FDG". J. Nucl. Med. 45 (6): 972–9. PMID 15181132.
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