Fenbufen
From Wikipedia, the free encyclopedia
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| Systematic (IUPAC) name | |
|---|---|
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4-(4-Biphenylyl)-4-oxobutanoic acid
or 4-Oxo-4-(4-phenylphenyl)butanoic acid |
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| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Routes of administration |
Oral |
| Legal status | |
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| Identifiers | |
| CAS Number | 36330-85-5 |
| ATC code | M01AE05 (WHO) |
| PubChem | CID 3335 |
| DrugBank | DB08981  |
| ChemSpider | 3218 |
| UNII | 9815R1WR9B |
| KEGG | D01344 |
| ChEBI | CHEBI:31599 |
| ChEMBL | CHEMBL277522 |
| Chemical data | |
| Formula | C16H14O3 |
| Molar mass | 254.2854 |
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Fenbufen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives class.[1]
It was introduced by American Cyanamid under the trade name Lederfen in the 1980s and was withdrawn from markets in the developed world due to liver toxicity in 2010.[2][3]:370, 383-384
As of 2015 it was available in Taiwan and Thailand under several brand names.[4]
References[edit]
- ^ Brogden RN. Non-steroidal anti-inflammatory analgesics other than salicylates. Drugs. 1986;32 Suppl 4:27-45. Review. PMID 3552584
- ^ Monthly Index of Medical Specialities Deleted products 2010
- ^ Lewis JH and Stine JG. Nonsteroidal Antiinflammatory Drugs and Leukotriene Receptor Antagonists. Chapter 22 in Drug-Induced Liver Disease, 3rd Edition. Eds Neil Kaplowitz N and DeLeve LD. Academic Press, 2013 ISBN 9780123878182
- ^ Drugs.com Drugs.com international listings for fenbufen Page accessed June 25, 2015
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