Sabcomeline
From Wikipedia, the free encyclopedia
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| Systematic (IUPAC) name | |
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(3R)-N-methoxyquinuclidine-3-carboximidoyl cyanide hydrochloride
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| Clinical data | |
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| Identifiers | |
| CAS Number | 159912-58-0 |
| ATC code | None |
| PubChem | CID 9577995 |
| IUPHAR/BPS | 306 |
| ChemSpider | 7852359 |
| UNII | P8P92V596C  |
| ChEMBL | CHEMBL134641 |
| Chemical data | |
| Formula | C10H15N3O |
| Molar mass | 193.12 g/mol |
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Sabcomeline (Memric; SB-202,026) is a selective M1 receptor partial agonist that was under development for the treatment of Alzheimer's disease.[1] It made it to phase III clinical trials before being discontinued due to poor results.
See also[edit]
References[edit]
- ^ Loudon JM, Bromidge SM, Brown F, et al. (December 1997). "SB 202026: a novel muscarinic partial agonist with functional selectivity for M1 receptors". The Journal of Pharmacology and Experimental Therapeutics 283 (3): 1059–68. PMID 9399977.
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