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Tetrindole

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Tetrindole
Tetrindole skeletal.svg
Systematic (IUPAC) name
2,3,3a,4,5,6-Hexahydro-8-cyclohexyl-1H-pyrazino[3,2,1-j,k]carbazole
Identifiers
ATC code None
PubChem CID 160020
ChemSpider 140675 YesY
ChEBI CHEBI:77799 N
Chemical data
Formula C20H26N2
Molar mass 294.43 g/mol
 NYesY (what is this?)  (verify)

Tetrindole was a drug candidate that functions by reversibly inhibiting monoamine oxidase A; it was first synthesized in Moscow in the early 1990s.[1] Tetrindole is similar in its chemical structure to pirlindole (Pyrazidol), and metralindole.[2]

References[edit]

  1. ^ Medvedev, AE; Kirkel, AA; Kamyshanskaya, NS; Moskvitina, TA; Axenova, LN; Gorkin, VZ; Andreeva, NI; Golovina, SM; Mashkovsky, MD (20 January 1994). "Monoamine Oxidase Inhibition by Novel Antidepressant Tetrindole". Biochemical Pharmacology 47 (2): 303–8. doi:10.1016/0006-2952(94)90021-3. PMID 8304974. 
  2. ^ Ramsay, RR; Gravestock, MB (March 2003). "Monoamine Oxidases: to Inhibit or Not to Inhibit". Mini Reviews in Medicinal Chemistry 3 (2): 129–36. PMID 12570845. 

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