Seproxetine

Seproxetine

Systematic (IUPAC) name
(S)-3-Phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
Clinical data
Routes of administration	Oral
Legal status	Uncontrolled
Pharmacokinetic data
Biological half-life	4-16 days
Identifiers
CAS Number	126924-38-7
ATC code	None
PubChem	CID 4541
IUPHAR/BPS	208
DrugBank	DB06731
ChemSpider	4382
UNII	25CO3X0R31 Y
Chemical data
Formula	C16H16F3NO
Molar mass	295.30 g/mol

Seproxetine, also known as (S)-norfluoxetine, is a selective serotonin reuptake inhibitor (SSRI). It is the most important active metabolite of the widely used antidepressant fluoxetine, but little is known about its pharmacological actions. Seproxetine was being investigated by Eli Lilly and Company as an antidepressant; however, a cardiac side effect was noted and development was discontinued.

References