Isothipendyl

Isothipendyl

Systematic (IUPAC) name
N,N-dimethyl-1-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propan-2-amine
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	482-15-5 1225-65-6
ATC code	D04AA22 R06AD09
PubChem	CID 3781
DrugBank	DB08802 Y
ChemSpider	3649 Y
UNII	WVZ7K9P0JY Y
KEGG	D08091 Y
Chemical data
Formula	C16H19N3S
Molar mass	285.408 g/mol
SMILES n2c1N(c3c(Sc1ccc2)cccc3)CC(N(C)C)C
InChI InChI=1S/C16H19N3S/c1-12(18(2)3)11-19-13-7-4-5-8-14(13)20-15-9-6-10-17-16(15)19/h4-10,12H,11H2,1-3H3 Y Key:OQJBSDFFQWMKBQ-UHFFFAOYSA-N Y
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Isothipendyl is a 1st generation H₁ antagonist (antihistamine) and anticholinergic used as an antipruritic. It is nowadays scarcely used in the 1st line relief of allergies due to the anticholinergic side effect of somnolence but does have some limited use through topical application in the relief of insect bites and related itching (pruritus).

See also

• Promethazine

References