Naftopidil

Naftopidil
Systematic (IUPAC) name
	1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-(1-naphthyloxy)propan-2-ol
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	℞ (Prescription only);
Routes of; administration	Oral
Identifiers
CAS Number	57149-07-2
ATC code	None
PubChem	CID: 4418
ChemSpider	4265
UNII	R9PHW59SFN
Chemical data
Formula	C24H28N2O3
Molecular mass	392.49 g/mol
	SMILES COC1=CC=CC=C1N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O ;
	InChI InChI=1S/C24H28N2O3/c1-28-24-11-5-4-10-22(24)26-15-13-25(14-16-26)17-20(27)18-29-23-12-6-8-19-7-2-3-9-21(19)23/h2-12,20,27H,13-18H2,1H3 ; Key:HRRBJVNMSRJFHQ-UHFFFAOYSA-N ;
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Naftopidil (INN, marketed under the brand name Flivas) is an antihypertensive drug which acts as a selective α₁-adrenergic receptor antagonist or alpha blocker.^[1]

References[edit]

^ Sakai H, Igawa T, Onita T, Furukawa M, Hakariya T, Hayashi M, Matsuya F, Shida Y, Nishimura N, Yogi Y, Tsurusaki T, Takehara K, Nomata K, Shiraishi K, Shono T, Aoki D, Kanetake H. (2011). "Efficacy of naftopidil in patients with overactive bladder associated with benign prostatic hyperplasia: prospective randomized controlled study to compare differences in efficacy between morning and evening medication". Hinyokika Kiyo. 57 (1): 7–13. PMID 21304253.

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