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Lpar4
Gene Detail
 Symbol
Name
ID
Lpar4
lysophosphatidic acid receptor 4
MGI:1925384
Synonyms 5730485F04Rik, Gpr23, LPA4, p2y9
Feature Type protein coding gene
Genetic Map
Chromosome X
47.39 cM
Detailed Genetic Map ± 1 cM

Mapping data(2)
Sequence Map
ChrX:104115964-104129239 bp, + strand
(From VEGA annotation of NCBI Build 37)

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Mammalian
homology 		human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Lpar4 ± 2 cM)

Protein SuperFamily: LPAR4-like receptor
Gene Tree: Lpar4
Human
ortholog 		LPAR4 lysophosphatidic acid receptor 4 NCBI Gene ID 2846
Human Synonyms: GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9
Human ChrX:78003206-78012588 bp, + strand Reference GRCh37.p2 Primary Assembly
Alleles
and
phenotypes 		All alleles(7) : Targeted(3) Gene trapped(4)
 
Mice homozygous for a knock-out allele exhibit prenatal lethality, edema, hemorrhage, dilated lymphatic vessels and lymph sacs, and dilated blood vessels with poor mural cell coverage.
 
Gene Ontology
(GO)
classifications 		All GO classifications: (12 annotations)
Process G-protein coupled purinergic nucleotide receptor signaling pathway, G-protein coupled receptor signaling pathway, ...
Component integral to membrane, membrane, ...
Function G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity, ...
External Resources: FuncBase
Expression Literature Summary: (6 records)
Data Summary: Results (222)    Tissues (39)    Images (24)
Theiler Stages: 20, 23
Assay TypeResults
RNA in situ 221
RT-PCR 1
cDNA source data(24)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents 		All nucleic(25) cDNA(24) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000018372 (Evidence)
Ensembl Gene ModelENSMUSG00000049929 (Evidence)
Entrez Gene78134 (Evidence)
UniGene90147
DFCITC1580334, TC1652212, TC1743023, TC1758420
DoTSDT.101386602, DT.40182399, DT.91587901, DT.94153554
NIA Mouse Gene IndexU020128
Consensus CDS ProjectCCDS30345.1
International Mouse Knockout Project StatusLpar4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018372 VEGA Gene Model | MGI Sequence Detail 13276 C57BL/6J ±  Kb
transcript OTTMUST00000044364 VEGA | MGI Sequence Detail 4238 Not Applicable 
polypeptide OTTMUSP00000019932 VEGA | MGI Sequence Detail 370 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(83 from dbSNP Build 128)
Protein-related
information
ResourceIDDescription
InterPro IPR000276 GPCR, rhodopsin-like, 7TM
InterPro IPR017452 GPCR, rhodopsin-like superfamily
InterPro IPR002188 P2Y5 purinoceptor
Protein Ontology PR:000001598 lysophosphatidic acid receptor 4
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(34)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/07/2012
MGI 5.10.03
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