Metanephrine

Metanephrine
Names
	IUPAC name 4-(1-hydroxy-2-methylamino-ethyl)-2-methoxy-phenol
Identifiers
CAS Number	5001-33-2
ChEMBL	ChEMBL775
ChemSpider	19844
IUPHAR/BPS	6644
Jmol interactive 3D	Image
MeSH	Metanephrine
PubChem	21100
	InChI InChI=1S/C10H15NO3/c1-11-6-9(13)7-3-4-8(12)10(5-7)14-2/h3-5,9,11-13H,6H2,1-2H3 Key: JWJCTZKFYGDABJ-UHFFFAOYSA-N ; InChI=1/C10H15NO3/c1-11-6-9(13)7-3-4-8(12)10(5-7)14-2/h3-5,9,11-13H,6H2,1-2H3 Key: JWJCTZKFYGDABJ-UHFFFAOYAB ;
	SMILES Oc1ccc(cc1OC)C(O)CNC ;
Properties
Chemical formula	C10H15NO3
Molar mass	197.231 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Metanephrine (metadrenaline) is a metabolite of epinephrine (adrenaline) created by action of catechol-O-methyl transferase on epinephrine. An article in the Journal of the American Medical Association, 2002, indicated that the measurement of plasma free levels of the metanephrines group of molecules (including metanephrine and normetanephrine) is the best tool in the diagnosis of pheochromocytoma, an adrenal medullary neoplasm.^[1]

References[edit]

^ Lenders J, Pacak K, Walther M, Linehan W, Mannelli M, Friberg P, Keiser H, Goldstein D, Eisenhofer G (2002). "Biochemical diagnosis of pheochromocytoma: which test is best?". JAMA 287 (11): 1427–34. doi:10.1001/jama.287.11.1427. PMID 11903030. Free full text with registration

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