Norcodeine
From Wikipedia, the free encyclopedia
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| Systematic (IUPAC) name | |
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3-Methoxy-6α-hydroxy-4,5α-epoxy-7,8-didehydromorphinan
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| CAS Number | 467-15-2  |
| ATC code | none |
| PubChem | CID 9925873 |
| ChemSpider | 8101508  |
| UNII | 32W9P3T4ML |
| Chemical data | |
| Formula | C17H19NO3 |
| Molar mass | 285.337 g/mol |
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Not to be confused with Norco (medication).
Norcodeine is an opiate analogue that is the N-demethylated derivative of codeine.
Norcodeine has relatively little opioid activity in its own right,[1] but is formed as a metabolite of codeine following ingestion.[2]
Norcodeine is a Schedule I Narcotic controlled substance in the USA with the ACSCN of 9309 and zero annual manufacturing quota. The salts in use are the acetate (free base conversion ratio 0.826), hydroiodide (0.662), hydrochloride (0.759), nitrate (0.819), platinichloride (0.582), and sulphate (0.744).[3]
References[edit]
- ^ Fraser HF, Isbell H, Van Horn GD. Human pharmacology and addiction liability of norcodeine. Journal of Pharmacology and Experimental Therapeutics. 1960 Jun;129:172-7. PMID 13824628
- ^ Posey BL, Kimble SN. High-performance liquid chromatographic study of codeine, norcodeine, and morphine as indicators of codeine ingestion. Journal of Analytical Toxicology. 1984 Mar-Apr;8(2):68-74. PMID 6716978.
- ^ http://www.deadiversion.usdoj.gov/fed_regs/quotas/2014/fr0825.htm
