Tolonidine
From Wikipedia, the free encyclopedia
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| Names | |
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| IUPAC name
N-(2-chloro-4-methylphenyl)-4,5-dihydro-1H-imidazol-2-amine
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| Identifiers | |
4201-22-3  |
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| Jmol interactive 3D | Image |
| KEGG | D07168 |
| PubChem | 72138 |
| UNII | I4O795Q03O |
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| Properties | |
| C10H12ClN3 | |
| Molar mass | 209.67538 |
| Pharmacology | |
| ATC code | C01 |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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| Infobox references | |
Tolonidine is an antihypertensive.[1][2][3]
References[edit]
- ^ Cosnier, D.; Duchene-Marullaz, P.; Grimal, J.; Rispat, G.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action on blood pressure and heart rate". Arzneimittel-Forschung 25 (10): 1557–1561. PMID 1243037.
- ^ Cosnier, D.; Labrid, C.; Rispat, G.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis". Arzneimittel-Forschung 25 (11): 1802–1806. PMID 1243090.
- ^ Cosnier, D.; Hache, J.; Labrid, C.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. III. Action on the secretions of the digestive tract and on the central nervous system, acute toxicity". Arzneimittel-Forschung 25 (12): 1926–1933. PMID 3186.
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