Trimazosin

Trimazosin
Systematic (IUPAC) name
	(2-hydroxy-2-methylpropyl) 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate
Identifiers
CAS Number	53746-46-6
ATC code	C02CA03
PubChem	CID: 37264
ChemSpider	34203
UNII	31L760807H
ChEMBL	CHEMBL513301
Chemical data
Formula	C20H29N5O6
Molecular mass	435.47 g/mol
	SMILES O=C(OCC(O)(C)C)N3CCN(c1nc(N)c2c(n1)c(OC)c(OC)c(OC)c2)CC3 ;
	InChI InChI=1S/C20H29N5O6/c1-20(2,27)11-31-19(26)25-8-6-24(7-9-25)18-22-14-12(17(21)23-18)10-13(28-3)15(29-4)16(14)30-5/h10,27H,6-9,11H2,1-5H3,(H2,21,22,23) ; Key:YNZXWQJZEDLQEG-UHFFFAOYSA-N ;
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Trimazosin is a sympatholytic alpha blocker.^[1]^[2]

References[edit]

^ van Kalken CK, van der Meulen J, Oe PL, Vriesendorp R, Donker AJ (1986). "Pharmacokinetics of trimazosin and its effects on blood pressure, renal function and proteinuria during short-term therapy of patients with impaired renal function and hypertension". Eur. J. Clin. Pharmacol. 31 (1): 63–8. doi:10.1007/BF00870988. PMID 3780829.
^ U.S. Patent 3,669,968

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