NAN-190

NAN-190

Systematic (IUPAC) name
1-(2-Methoxyphenyl)-4-(4-phthalimidobutyl)piperazine
Identifiers
CAS Number	115388-32-4 Y
PubChem	CID: 4431
IUPHAR/BPS	73
ChemSpider	4278 N
ChEMBL	CHEMBL8618 N
Chemical data
Formula	C23H27N3O3
Molecular mass	393.478 g/mol
SMILES O=C1c2ccccc2C(=O)N1CCCCN4CCN(CC4)c3ccccc3OC
InChI InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3 N Key:SJDOMIRMMUGQQK-UHFFFAOYSA-N N
NY (what is this?)  (verify)

NAN-190 is a drug and research chemical widely used in scientific studies. It was previously believed to act as a selective 5-HT_1A receptor antagonist, but a subsequent discovery showed that it also potently blocks the α₂-adrenergic receptor. The new finding has raised significant concerns about studies using NAN-190 as a specific serotonin receptor antagonist.

References