2,3-Dichlorophenylpiperazine
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This article is about the chemical compound. For the Disease Control Priorities Project, see Disease Control Priorities Project.
| Names | |
|---|---|
| IUPAC name
1-(2,3-dichlorophenyl)piperazine
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| Identifiers | |
| 41202-77-1 |
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| ChemSpider | 744460 |
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| Jmol interactive 3D | Image |
| PubChem | 851833 |
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| Properties | |
| C10H12Cl2N2 | |
| Molar mass | 231.12 g/mol |
| Appearance | brown oil |
| Density | 1.272g/cm3 °C |
| Melting point | 242 to 244 °C (468 to 471 °F; 515 to 517 K) |
| Boiling point | 365.1 °C (689.2 °F; 638.2 K) at 760mmHg |
| Hazards | |
| Flash point | 174.6 °C (346.3 °F; 447.8 K) |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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| Infobox references | |
2,3-Dichlorophenylpiperazine (2,3-DCPP or DCPP) is a chemical compound. It is both a precursor in the synthesis of aripiprazole and one of its metabolites.[1][2] It is unknown whether 2,3-DCPP is pharmacologically active similar to its close analogue 3-chlorophenylpiperazine (mCPP).
Chemical derivatives[edit]
See also[edit]
References[edit]
- ^ Leś A, Badowska-Rosłonek K, Łaszcz M, Kamieńska-Duda A, Baran P, Kaczmarek Ł (2010). "Optimization of aripiprazole synthesis". Acta Poloniae Pharmaceutica 67 (2): 151–7. PMID 20369792.
- ^ Caccia S (August 2007). "N-dealkylation of arylpiperazine derivatives: disposition and metabolism of the 1-aryl-piperazines formed". Current Drug Metabolism 8 (6): 612–22. doi:10.2174/138920007781368908. PMID 17691920.
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