Clorgiline

Clorgiline
Systematic (IUPAC) name
	N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-prop-2-yn-1-amine
Clinical data
Legal status	Uncontrolled;
Identifiers
CAS Number	17780-72-2
ATC code	None
PubChem	CID 4380
IUPHAR/BPS	6636
DrugBank	DB04017
ChemSpider	4227
UNII	LYJ16FZU9Q
KEGG	D03248
ChEBI	CHEBI:3763
ChEMBL	CHEMBL8706
Chemical data
Formula	C13H15Cl2NO
Molar mass	272.17 g/mol
	SMILES Clc1cc(Cl)ccc1OCCCN(CC#C)C ;
	InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3 ; Key:BTFHLQRNAMSNLC-UHFFFAOYSA-N ;
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Clorgiline is a monoamine oxidase inhibitor (MAOI). Specifically, it is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A). It is used in scientific research.^[1] It is structurally related to pargyline.

References[edit]

^ Murphy, D. L.; Karoum; Pickar; Cohen; Lipper; Mellow; Tariot; Sunderland (1998). "Differential trace amine alterations in individuals receiving acetylenic inhibitors of MAO-A (clorgyline) or MAO-B (selegiline and pargyline)". Journal of neural transmission. Supplementum. Journal of Neural Transmission. Supplement 52: 39–48. doi:10.1007/978-3-7091-6499-0_5. ISBN 978-3-211-83037-6. PMID 9564606.