Nafadotride
From Wikipedia, the free encyclopedia
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| Names | |
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| IUPAC name
N-{[(2S)-1-butylpyrrolidin-2-yl]methyl}-4-cyano-1-methoxy-2-naphthamide
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| Identifiers | |
149649-22-9  |
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| ChEMBL | ChEMBL286252  |
| 44 | |
| Jmol interactive 3D | Image |
| MeSH | Nafadotride |
| PubChem | 3408722 |
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| Properties | |
| C22H27N3O2 | |
| Molar mass | 365.48 g·mol−1 |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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 verify (what is ?) |
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| Infobox references | |
Nafadotride is a dopamine antagonist with reasonable selectivity for the D3 subtype (9.6 times selectivity for D3 over D2).[1]
References[edit]
- ^ Pilla M, Perachon S, Sautel F, Garrido F, Mann A, Wermuth CG, Schwartz JC, Everitt BJ, Sokoloff P. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 agonist. Nature. 1999;400:371–375.
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