Cyanopindolol

Cyanopindolol
Systematic (IUPAC) name
	(RS)-4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carbonitrile
Identifiers
CAS Number	69906-85-0
ATC code	None
PubChem	CID: 155346
IUPHAR/BPS	132
ChemSpider	136847
ChEMBL	CHEMBL378501
Chemical data
Formula	C16H21N3O2
Molecular mass	287.36 g/mol
	SMILES N#CC1=CC2=C(OCC(CNC(C)(C)C)O)C=CC=C2N1 ;
	InChI InChI=1S/C16H21N3O2/c1-16(2,3)18-9-12(20)10-21-15-6-4-5-14-13(15)7-11(8-17)19-14/h4-7,12,18-20H,9-10H2,1-3H3 ; Key:QXIUMMLTJVHILT-UHFFFAOYSA-N ;
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Cyanopindolol (INN) is a drug related to pindolol which acts as both a β₁ adrenoceptor antagonist and a 5-HT_1A receptor antagonist. Its radiolabelled derivative iodocyanopindolol has been widely used in mapping the distribution of beta adrenoreceptors in the body.^[1]

References[edit]

^ Hoyer, D.; Engel, G. (1983). "Binding of 125I-cyanopindolol to beta-1-adrenoceptors in a high and low affinity state". Journal of Receptor Research 3 (1-2): 45–59.

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Systematic (IUPAC) name


(RS)-4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carbonitrile
Identifiers
CAS Number	69906-85-0^Y
ATC code	None
PubChem	CID: 155346
IUPHAR/BPS	132
ChemSpider	136847^N
ChEMBL	CHEMBL378501^N
Chemical data
Formula	C₁₆H₂₁N₃O₂
Molecular mass	287.36 g/mol
SMILES N#CC1=CC2=C(OCC(CNC(C)(C)C)O)C=CC=C2N1
InChI InChI=1S/C16H21N3O2/c1-16(2,3)18-9-12(20)10-21-15-6-4-5-14-13(15)7-11(8-17)19-14/h4-7,12,18-20H,9-10H2,1-3H3^N Key:QXIUMMLTJVHILT-UHFFFAOYSA-N^N
^NY (what is this?) (verify)