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Dopamine releasing agent

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A dopamine releasing agent (DRA) is a type of drug which induces the release of dopamine in the body and/or brain.

No selective DRAs are currently known. Many releasing agents of both dopamine and norepinephrine (norepinephrine-dopamine releasing agents, or NDRAs) and of serotonin, norepinephrine, and dopamine are known (serotonin-norepinephrine-dopamine releasing agents, or SNDRAs), however. Examples of NDRAs include amphetamine and methamphetamine, and an example of an SNDRA is MDMA. These drugs are frequently encountered as drugs of abuse.

A closely related type of drug is a dopamine reuptake inhibitor (DRI). Various selective DRIs are known, in contrast to the case of DRAs.

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