Dimaprit
From Wikipedia, the free encyclopedia
| Names | |
|---|---|
| IUPAC name
3-(dimethylamino)propyl carbamimidothioate
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| Other names
3-dimethylaminopropyl sulfanylmethanimidamide
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| Identifiers | |
| 65119-89-3 |
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| ChEMBL | ChEMBL12344 |
| ChemSpider | 2968 |
| 1248 | |
| Jmol interactive 3D | Image |
| KEGG | C17930 |
| PubChem | 3077 |
| UNII | ZZQ699148P |
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| Properties | |
| C6H15N3S | |
| Molar mass | 161.2684 g/mol |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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| Infobox references | |
Dimaprit is a histamine analog working as a selective H2 histamine receptor agonist.[1][2][3]
References[edit]
- ^ Kartzung, Betram G.; Trevor, Anthony J., eds. (2014). Basic and Clinical Pharmacology (13th ed.). New York: McGraw-Hill Education. p. 364. ISBN 0071825053.
- ^ Kohno, S; Ogawa, K; Nabe, T; Yamamura, H; Ohata, K (May 1993). "Dimaprit, a Histamine H2-agonist, Inhibits Anaphylactic Histamine Release from Mast Cells and the Decreased Release is Restored by Thioperamide (H3-antagonist), but not by Cimetidine (H2-antagonist)". Japanese Journal of Pharmacology 62 (1): 75–9. PMID 7688057.
- ^ Nakamura, T; Ueno, Y; Goda, Y; Nakamura, A; Shinjo, K; Nagahisa, A (March 1997). "Efficacy of a Selective Histamine H2 Receptor Agonist, Dimaprit, in Experimental Models of Endotoxin Shock and Hepatitis in Mice". European Journal of Pharmacology 322 (1): 83–89. doi:10.1016/S0014-2999(96)00987-9.

