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Pindobind

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Pindobind
Pindobind.svg
Names
IUPAC name
2-Bromo-N-[4-(2-{[2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino}-2-propanyl)-1-methylcyclohexyl]acetamide
Identifiers
106469-52-7 YesY
ChemSpider 4661
Jmol interactive 3D Image
PubChem 4827
Properties
C23H34BrN3O3
Molar mass 480.45 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Pindobind is a chemical patented by IBM.[1]It has experimentally been identified as a central nervous system depressant[2] which generated a response in animals of reducing offensive actions such as chasing, while also notably reducing tendencies of the test animal to evade when stimulated to do so.[2] It acts as an irreversible beta blocker and irreversible 5-HT1A receptor antagonist.

See also[edit]

References[edit]

  1. ^ CID 4827 from PubChem
  2. ^ a b Bell, R; Hobson, H (1993). "Effects of pindobind 5-hydroxytryptamine1A (5-HT1A), a novel and potent 5-HT1A antagonist, on social and agonistic behaviour in male albino mice". Pharmacology, Biochemistry, and Behavior 46 (1): 67–72. doi:10.1016/0091-3057(93)90318-N. PMID 8255924. 


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