Mepivacaine
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| Systematic (IUPAC) name | |
|---|---|
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(RS)-N-(2,6-dimethylphenyl)- 1-methyl-piperidine-2-carboxamide
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| Clinical data | |
| AHFS/Drugs.com | Consumer Drug Information |
| MedlinePlus | a603026 |
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| Identifiers | |
| CAS Registry Number | 96-88-8  |
| ATC code | N01BB03 |
| PubChem | CID: 4062 |
| IUPHAR/BPS | 7224 |
| DrugBank | DB00961 |
| ChemSpider | 3922 |
| UNII | B6E06QE59J |
| KEGG | D08181 |
| ChEBI | CHEBI:6759 |
| ChEMBL | CHEMBL1087 |
| Chemical data | |
| Formula | C15H22N2O |
| Molecular mass | 246.348 g/mol |
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Mepivacaine /mɛˈpɪvəkeɪn/ is a local anesthetic[1] of the amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine) and is marketed under various trade names including Carbocaine and Polocaine.
Mepivacaine became available in the United States in the 1960s.
Mepivacaine is used in any infiltration and regional anesthesia.
It is supplied as the hydrochloride salt of the racemate.[2]
References[edit]
- ^ Porto GG, Vasconcelos BC, Gomes AC, Albert D (January 2007). "Evaluation of lidocaine and mepivacaine for inferior third molar surgery" (PDF). Med Oral Patol Oral Cir Bucal 12 (1): E60–4. PMID 17195831.
- ^ Burm AG, Cohen IM, van Kleef JW, Vletter AA, Olieman W, Groen K (January 1997). "Pharmacokinetics of the enantiomers of mepivacaine after intravenous administration of the racemate in volunteers". Anesth. Analg. 84 (1): 85–9. doi:10.1097/00000539-199701000-00016. PMID 8989005.
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