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Gpr19
Gene Detail
Symbol

Name
ID
Gpr19
G protein-coupled receptor 19
MGI:892973
Feature Type
protein coding gene
Genetic Map
Chromosome 6
65.77 cM, cytoband G1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:134869108-134897925 bp, - strand
From VEGA annotation of GRCm38

  28818 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4476  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GPR19
Protein SuperFamily: probable G protein-coupled receptor 19
Gene Tree: Gpr19

Human
homologs
GPR19, G protein-coupled receptor 19
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 2842
neXtProt AC: NX_Q15760

Human Chr (Location): 12p12.3; chr12:12660884-12717272 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(61) : Gene trapped(57) Targeted(4)
Incidental mutations (data from APF )
 
Homozygous mutation of this gene results in increased anxiety-like behavior.
 
Interactions
Gpr19 interacts with 33 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process cell surface receptor signaling pathway, G-protein coupled receptor signaling pathway, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function G-protein coupled receptor activity, signal transducer activity
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (357)    Tissues (121)    Images (74)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 148
In situ reporter (knock in) 89
RT-PCR 120
cDNA source data(18)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase gpr19 ; ZFIN gpr19    NEW 
Molecular
reagents
All nucleic(21) cDNA(18) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000024355 (Evidence)
Ensembl Gene Model ENSMUSG00000032641 (Evidence)
Entrez Gene 14760 (Evidence)
UniGene 4787
DFCI TC1583398, TC1632077, TC1635617, TC1639727, TC1672891, TC1773976
DoTS DT.101257016, DT.101325547, DT.101374062, DT.101374063, DT.40168864, DT.91578631, DT.97391599, DT.99832479
NIA Mouse Gene Index U027958
Consensus CDS Project CCDS20641.1, CCDS51937.1
International Mouse Phenotyping Consortium Status Gpr19
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024355 VEGA Gene Model | MGI Sequence Detail 28818 C57BL/6J ±  kb
transcript OTTMUST00000059660 VEGA | MGI Sequence Detail 1610 Not Applicable 
polypeptide OTTMUSP00000029039 VEGA | MGI Sequence Detail 415 Not Applicable 

For the selected sequences
All sequences(89) RefSeq(31) UniProt(1)
Polymorphisms
SNPs within 2kb(326 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001520 G-protein coupled receptor 19
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:174767 Tang F, et al., Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
All references(38)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
08/25/2015
MGI 6.0 		The Jackson Laboratory
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