Potassium canrenoate

Potassium canrenoate
Systematic (IUPAC) name
	potassium 3-[(8R,9S,10R,13S,14S,17R)-; 17-hydroxy-10,13-dimethyl-3-oxo-2,8,9,; 11,12,14,15,16-octahydro-1H-cyclopenta[a]; phenanthren-17-yl]propanoate
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Intravenous
Pharmacokinetic data
Metabolism	Hepatic
Excretion	Renal and fecal
Identifiers
CAS Registry Number	2181-04-6
ATC code	C03DA02
PubChem	CID: 656614
DrugBank	DB09015
ChemSpider	570975
UNII	M671F9NLEA
ChEMBL	CHEMBL1371200
Synonyms	SC-14266
Chemical data
Formula	C22H29KO4
Molecular mass	396.5616 g/mol
	SMILES [K+].[O-]C(=O)CC[C@]3(O)CC[C@H]2[C@@H]4/C=C\C1=C\C(=O)CC[C@@]1([C@H]4CC[C@@]23C)C ;
	InChI InChI=1S/C22H30O4.K/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21,26)12-8-19(24)25;/h3-4,13,16-18,26H,5-12H2,1-2H3,(H,24,25);/q;+1/p-1/t16-,17+,18+,20+,21+,22-;/m1./s1 ; Key:JTZQCHFUGHIPDF-RYVBEKKQSA-M ;
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Potassium canrenoate (INN, JAN) or canrenoate potassium (USAN) (brand names Venactone, Soldactone), the potassium salt of canrenoic acid, is an aldosterone antagonist.^[1] Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body. Potassium canrenoate is not licensed in the UK, but may sometimes be prescribed off-licence to treat oedema. It is given intravenously.

References[edit]

^ R.A. Hill; H.L.J. Makin; D.N. Kirk; G.M. Murphy (23 May 1991). Dictionary of Steroids. CRC Press. pp. 656–. ISBN 978-0-412-27060-4.

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Systematic (IUPAC) name

potassium 3-[(8R,9S,10R,13S,14S,17R)- 17-hydroxy-10,13-dimethyl-3-oxo-2,8,9, 11,12,14,15,16-octahydro-1H-cyclopenta[a] phenanthren-17-yl]propanoate
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Intravenous
Pharmacokinetic data
Metabolism	Hepatic
Excretion	Renal and fecal
Identifiers
CAS Registry Number	2181-04-6^N
ATC code	C03DA02
PubChem	CID: 656614
DrugBank	DB09015^N
ChemSpider	570975^Y
UNII	M671F9NLEA^N
ChEMBL	CHEMBL1371200^N
Synonyms	SC-14266
Chemical data
Formula	C₂₂H₂₉K O₄
Molecular mass	396.5616 g/mol
SMILES [K+].[O-]C(=O)CC[C@]3(O)CC[C@H]2[C@@H]4/C=C\C1=C\C(=O)CC[C@@]1([C@H]4CC[C@@]23C)C
InChI InChI=1S/C22H30O4.K/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21,26)12-8-19(24)25;/h3-4,13,16-18,26H,5-12H2,1-2H3,(H,24,25);/q;+1/p-1/t16-,17+,18+,20+,21+,22-;/m1./s1^Y Key:JTZQCHFUGHIPDF-RYVBEKKQSA-M^Y
N (what is this?) (verify)